The newly released Photoshop Generator feature works awesome with Adobe Edge Reflow. I used it to redesign my site. I was very happy and very productive. However when I first launched this, I ran into an issue where it didn’t work the way I thought it was. Basically I thought that the magic was miraculous instead of just incredibly cool. When you first convert a PSD to Reflow you have to take a moment and organize the Reflow project before you start designing a set of responsive layouts. Once you get how Photoshop exports, it makes sense. But at first you have to do some work for yourself. I have a video showing how to do this.
The video will also take you through adding Typekit support to a generated Reflow project.
Hope this helps!